Treponema Pallidum Immune-adherence and Haemagglutination

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Treponema pallidum immune-adherence and haemagglutination.

According to Nelson (1953), " the immune-adherence phenomenon" is concerned with the specific attachment which occurs between erythrocytes and micro-organisms which are sensitized by antibody (Ab) and Complement (C'). Measurements of immune-adherence (IA) may be performed by counting the Treponema pallida remaining in the fluid phase of reaction mixtures containing T. pallida, Ab, C', and eryth...

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Appraisal of the Treponema pallidum haemagglutination test.

Several attempts have been made to use haemagglutination reactions for the diagnosis of syphilis between 1932 and 1958. The first reliable method was developed by Rathlev (1965). Further results of investigations with this method have been reported by authors from Japan and from the Venereal Disease Research Laboratory in Atlanta, U.S.A. Rathlev prepared the reagents for the test in the Statens...

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Treponema pallidum specific IgM haemagglutination test for serodiagnosis of syphilis.

The Treponema pallidum specific IgM haemagglutination (TP-IgM-HA) test uses erythrocytes sensitised with antiserum to human IgM to separate IgM from IgG in serum. Specific antitreponemal IgM captured in this way is detected by adding a second reagent comprising erythrocytes sensitised with T pallidum antigen. Eighty two serum samples from 82 patients with untreated syphilis, 521 samples from 73...

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Clinical value of the Treponema pallidum haemagglutination test.

In 1,129 patients attending the Department for Sexually Transmitted Diseases, the serum was examined by three screening tests (VDRL slide, RPCF, and TPHA) and twelve cases of syphilis (1 per cent. of patients attenting the clinic) were discovered. Six of these patients were considered to have latent syphilis (5 acquired, 1 congenital) and were detected only by the TPHA; all six cases were confi...

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Treponema pallidum immune adherence test for serodiagnosis of syphilis. 3: Clinical significance and evaluation of treatment.

Antibody titres were measured in patients with clinical syphilis, and the effect of treatment on the results of the Treponema pallidum immune adherence (TPIA) test is reported. In the Treponema pallidum haemagglutination (TPHA) test little change in antibody titre occurred after treatment while in the fluorescent treponemal antibody-absorbed (FTA-ABS) test only a slight decrease occurred. The d...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1956

ISSN: 1368-4973

DOI: 10.1136/sti.32.2.96